Physical Education
Fatemeh Akbari Vargsaran; Ameneh Pourrahim Ghoroghchi
Abstract
Introduction: Osteocalcin and osteopontin are related to diabetes and osteoporosis. The aim was to determine the effect of eight weeks of endurance-resistance training and taurine supplementation on osteocalcin and osteopontin in diabetic male Wistar rats.Materials and Methods: In this experimental study,40adult ...
Read More
Introduction: Osteocalcin and osteopontin are related to diabetes and osteoporosis. The aim was to determine the effect of eight weeks of endurance-resistance training and taurine supplementation on osteocalcin and osteopontin in diabetic male Wistar rats.Materials and Methods: In this experimental study,40adult male Wistar rats weighing 250-300grams and 6weeks old were randomly divided into 3 diabetic groups (each group, 10Rat); exercise, supplement and a control and a non-diabetic groups were included as a healthy control group. To make diabetic, 55mg/kg of body weight of streptozocin was injected. Combined exercises were performed for eight weeks and 5times a week. Taurine supplementation was taken as a 1% solution in water daily. One-way ANOVA and Bonferroni's post hoc were used to compare the inter-group and intra-group changes of the variables.Results: Osteocalcin increased significantly in the diabetic exercise group compared to the diabetic control (P=0.018) and decreased significantly in the diabetic control compared to the healthy (P=0.0001). Osteopontin increased significantly in the diabetic control group compared to the healthy control (P=0.003); While, there was no significant difference in other groups (P=1.000). Body weight and BMI increased significantly in the exercise-diabetic group compared to the diabetic-supplement (P=0.0001). There was a significant decrease in food consumption in the diabetic exercise group compared to the diabetic supplement group (P=0.030).Conclusion: Eight weeks of endurance-resistance training and taurine supplementation led to an increase in osteocalcin and no change in osteopontin.